The term off-label use refers to use of a drug that is not included in the package insert approved labeling for that drug.

Example of off-label drug use. Examples of treatments used off-label. In response to this practice gap The American Academy of Pediatrics adopted a policy statement on the use of off-label medications in children. Unapproved use of an approved drug is often called off-label use.

Antipsychotics are increasingly being used for off-label purposes and quetiapine Seroquel is the most common among them. In the past large drug manufacturers have been fined by the Justice Department for intentionally marketing their drugs for off-label use exposing patients and doctors to undue risk. Off-label use may occur for a variety of reasons.

For example methotrexate is commonly used off-label because its immunomodulatory effects relieve various disorders. Doctors may have found that the medicine works very well for this illness or condition. Migraines depression nerve pain.

Class of Drug. Dementia depression generalized anxiety disorder OCD. Of adverse events were higher with off-label use as compared with on-label use.

One study Radley et al. Examples of off-label drug use Doctors prescribe many different drugs for off-label use. Problematic Off-Label Drug Use.

This term can mean that the drug is. This use may be supported by expert groups but the drug manufacturer has not extended the licence. Used for a disease or medical condition that it is not approved to treat such as when a.