There is no consensus on how to define very low LDL cholesterol but LDL would be considered very low if it is less than 40 milligrams per deciliter of blood.
Can ldl go too low. Some patients such as those who started with an LDL cholesterol less than 70 mgdL achieved on-treatment LDL cholesterol levels as low as 24 mgdL. However data is lacking in terms of what the true adverse effects if any are of going too low for LDL levels and the trials took place when LDL target goals were of priority. Apparent relationships sometimes reported between less pronounced low LDL-C levels and disease states such as cancer depression infectious disease and others can generally be explained as secondary phenomena.
You cant go to either extreme too high or too low Doctors typically recommend that patients get their LDL cholesterol levels below 100 milligrams per deciliter. Data regarding the impact of lowering LDL-C with neurocognitive disorders are contradictory. Therefore an extremely low LDL by itself does not appear to be dangerous in these unusual cases.
However very low LDL cholesterol levels can be defined as levels below 40 milligrams per deciliter of blood. Cholesterol levels are considered to be low when they are significantly below the normal levels of 100 mgdL. Theres never been any evidence from any clinical trials showing a hazard of very low LDL cholesterol levels.
Patients at high risk of heart problems are often put on cholesterol lowering drugs to ensure their. However people with rare inherited disorders in which LDL levels are extremely low often less than 30 mgdL from birth appear to have normal fertility and no major organ dysfunction. Possible risks of extremely low levels J Intern Med.
Of importance cancer and hemorrhagic stroke incidences were not increased in patients attaining LDL-C lower than 40-50 mgdl. Although the risks are rare very low levels of LDL cholesterol may be associated with an increased risk of. Debating the benefits of ultra-low low-density lipoprotein LDL.
However because cholesterol is a major constituent of the brain too lower LDL cholesterol levels may impair neurocognitive function dementia and Alzheimers disease despite of reduction of cardiovascular disease. But at the same time the new findings suggest that levels of LDL cholesterol that are too low in this case less than 70 mgdL are also detrimental in this particular population by. Traditionally an LDL cholesterol level of more than 100 mgdl had been considered as optimal for the general population and lower in individuals at elevated risk of.